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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
REXO4
All Species:
12.73
Human Site:
S46
Identified Species:
21.54
UniProt:
Q9GZR2
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9GZR2
NP_065118.2
422
46672
S46
K
S
K
A
R
E
V
S
K
K
P
A
S
G
P
Chimpanzee
Pan troglodytes
XP_528522
404
44489
S46
K
S
K
A
Q
E
V
S
K
K
P
A
S
G
P
Rhesus Macaque
Macaca mulatta
XP_001101121
422
46500
S46
K
S
K
A
Q
E
V
S
K
K
P
G
S
G
P
Dog
Lupus familis
XP_548392
428
46939
E44
S
N
R
R
A
A
S
E
G
A
G
G
G
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q6PAQ4
432
47580
F50
R
K
K
A
K
K
K
F
R
K
S
K
A
L
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508485
438
48720
E55
T
K
A
R
E
G
G
E
K
Q
K
G
S
H
K
Chicken
Gallus gallus
XP_001236410
416
45873
N44
K
Q
K
A
S
T
S
N
E
P
L
P
S
A
Q
Frog
Xenopus laevis
Q91560
421
46679
T44
Q
N
H
P
K
I
T
T
K
T
G
E
T
K
K
Zebra Danio
Brachydanio rerio
XP_002665913
418
47625
G61
F
I
M
P
P
T
D
G
Q
D
Y
S
C
N
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396691
278
32474
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794891
360
40175
S46
A
T
S
D
K
E
T
S
K
E
D
K
S
N
I
Poplar Tree
Populus trichocarpa
XP_002300407
274
31114
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08237
289
32876
Red Bread Mold
Neurospora crassa
Q7S9B7
406
43643
E45
S
K
K
S
I
S
S
E
T
L
K
R
K
A
E
Conservation
Percent
Protein Identity:
100
94.3
93.1
68.4
N.A.
67.5
N.A.
N.A.
55.7
49
50.7
45
N.A.
N.A.
34.1
N.A.
35.7
Protein Similarity:
100
95.5
95.9
77.3
N.A.
77.5
N.A.
N.A.
68
63.2
67.3
60.9
N.A.
N.A.
47.3
N.A.
53
P-Site Identity:
100
93.3
86.6
0
N.A.
20
N.A.
N.A.
13.3
26.6
6.6
0
N.A.
N.A.
0
N.A.
26.6
P-Site Similarity:
100
100
93.3
13.3
N.A.
53.3
N.A.
N.A.
20
40
40
13.3
N.A.
N.A.
0
N.A.
46.6
Percent
Protein Identity:
32.2
N.A.
N.A.
N.A.
28.6
26.7
Protein Similarity:
45
N.A.
N.A.
N.A.
43.8
47.6
P-Site Identity:
0
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
0
N.A.
N.A.
N.A.
0
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
36
8
8
0
0
0
8
0
15
8
15
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
8
0
0
8
0
0
8
8
0
0
0
0
% D
% Glu:
0
0
0
0
8
29
0
22
8
8
0
8
0
0
8
% E
% Phe:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
8
8
8
0
15
22
8
22
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
8
0
0
8
8
0
0
0
0
0
0
0
0
8
% I
% Lys:
29
22
43
0
22
8
8
0
43
29
15
15
8
8
15
% K
% Leu:
0
0
0
0
0
0
0
0
0
8
8
0
0
8
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
15
0
0
0
0
0
8
0
0
0
0
0
15
0
% N
% Pro:
0
0
0
15
8
0
0
0
0
8
22
8
0
0
22
% P
% Gln:
8
8
0
0
15
0
0
0
8
8
0
0
0
0
8
% Q
% Arg:
8
0
8
15
8
0
0
0
8
0
0
8
0
8
8
% R
% Ser:
15
22
8
8
8
8
22
29
0
0
8
8
43
0
0
% S
% Thr:
8
8
0
0
0
15
15
8
8
8
0
0
8
0
0
% T
% Val:
0
0
0
0
0
0
22
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _